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A citation index is built on the fact that citations in science serve as linkages between similar research items, and lead to matching or related scientific literature, such as journal articles, conference proceedings, abstracts, etc. Citations are the formal, explicit linkages between papers that have particular points in common. A citation index is built around these linkages. It lists publications that have been cited and identifies the sources of the citations.

Anyone conducting a literature search can find from one to dozens of additional papers on a subject just by knowing one that has been cited. Web of Science is described as a unifying research tool that enables the user to acquire, analyze, and disseminate database information in a timely manner. This is accomplished because of the creation of a common vocabulary, called ontology, for varied search terms and varied data. Moreover, search terms generate related information across categories. Acceptable content for Web of Science is determined by an evaluation and selection process based on the following criteria: impact, influence, timeliness, peer review, and geographic representation. Web of Science employs various search and analysis capabilities.